Evolution of therapy for D-transposition of the great arteries.

Historical Evolution of Surgery for Transposition of Great Arteries (TGA)

The science and art of cardiac surgery has made rapid development in the past 65 years. The surgery for transposition of great arteries (TGA) symbolises the manner in which cardiac surgery has progressed. The eventually successful solution in the form of the now popular arterial switch operation (ASO) was elucidated after multiple contributions from several surgical stalwarts and geniuses over ...

Transposition of the great arteries

Transposition of the great arteries (TGA), also referred to as complete transposition, is a congenital cardiac malformation characterised by atrioventricular concordance and ventriculoarterial (VA) discordance. The incidence is estimated at 1 in 3,500-5,000 live births, with a male-to-female ratio 1.5 to 3.2:1. In 50% of cases, the VA discordance is an isolated finding. In 10% of cases, TGA is ...

Transposition of the great arteries.

Many patients with ventriculoarterial discordance have survived to adulthood. Those with complete transposition of the great arteries have often had an atrial switch procedure (Mustard or Senning operation) performed, which leaves the morphological right ventricle (RV) supporting the systemic circulation. RV failure and tricuspid regurgitation are common. Some patients may ultimately require ca...

Transposition of the great arteries.

Transposition of the Great Arteries

A nonsurgical method of creating atrial septal defects using a balloon catheter has been reviewed, and important procedural and technical details have been presented. The results of balloon atrioseptostomy in 31 infants with transposition of the great arteries have been reported and compared with those from the surgical creation of atrial septal defects. All 31 patients survived balloon atriose...